HeLa® MESO BOTO‑Xtreme+ MASTER COURSE
A groundbreaking new treatment with a botulinum‑like effect that is not physician‑restricted.
Get certified on the MESO BOTO‑Xtreme+ Master Course and offer advanced, non‑invasive anti‑aging treatments with documented results
Offer advanced, non‑surgical anti‑aging with proven results
While many treatments promise quick fixes without real skin improvement, the MESO BOTO‑Xtreme+ Master Course gives you access to an evidence‑based method that reduces fine lines, firms the skin and delivers visible, lasting effects.
As a certified Mesoskinline® mesotherapist you gain the competencies to work with advanced, non‑invasive techniques — safely and effectively, without surgery or lasers.
Designed for practitioners who want to go beyond classic facials and offer results grounded in science, high professional standards and long‑term rejuvenation.
Non‑invasive mesotherapy — targeted smoothing with peptides
MESO BOTO‑Xtreme+ delivers an advanced peptide cocktail precisely where the skin needs it — without injections, lasers or surgery. The formulation helps relax expression lines, improve elasticity and even skin tone.
Gentle technique — high impact.
This treatment works purely non‑invasively without compromising the skin barrier. It stimulates natural regeneration and improves both surface texture and firmness for a calmer, smoother look.
Suitable for many skin types.
An excellent option for clients who are not candidates for classic microneedling or who prefer a needle‑ and toxin‑free alternative. Comfortable, no downtime, and a luxurious anti‑aging effect with visible improvements in glow, tone and contour.
Certified mesotherapist — safety, knowledge and measurable results for your clinic
MESO BOTO‑Xtreme+ is your gateway to advanced non‑invasive mesotherapy.
No prior mesotherapy experience is required. The program is structured, safe and suitable both as an upgrade for experienced practitioners and as an introduction for beauticians, clinic owners and others who wish to add documented anti‑aging expertise.
Gain the theory and practical skills to work professionally with peptide‑based meso cocktails that reduce expression lines and improve skin structure — helping you differentiate your clinic with science‑based treatments and build loyalty and long‑term value.
CPD CERTIFICATE 
AWARDED AFTER COMPLETION
Products Starter Kit for up to 10/20 treatments
Products included in this Online Training Course
- 24 × 3.5 ml Meso Pure Peel
- 10 × Meso Anti‑Age mask
- 1 × Meso Lift and Protect
- 2 boxes of Spheracoll
- 1 × MESO BOTO‑Xtreme+ (10 ml vial) — for 10–20 treatments
- 10 × sterile syringes (for product withdrawal in non‑invasive method)
- 10 × sterile hypodermic needles (for product withdrawal in non‑invasive method)
Starter Kit box & MesoPower Pen (if checked) will be delivered to your address within 3-5 days after checkout of the course.
MESO BOTO‑Xtreme+ Master Course — demonstrable anti‑aging results without medical authorisation
A groundbreaking treatment with a botulinum‑like effect.
If you want to offer treatments that deliver significant, long‑lasting anti‑aging effects — comparable to Botox‑like results but without injections and without physician licensing — this course is for you.
We are the only provider worldwide offering this advanced program where professional practitioners learn a revolutionary non‑invasive anti‑aging method using MESO BOTO‑Xtreme+.
Who can perform the treatment?
When performed by a non‑invasive method, MESO BOTO‑Xtreme+ is not physician‑restricted. Qualified professionals such as beauticians, mesotherapists, PMU artists and other trained practitioners can offer it.
How is it performed?
Using the MESOpower® Pen with dedicated modules:
- MESO 11‑Point Micro Module
- MESO 3‑Point Nano Module
These deliver MESO BOTO‑Xtreme+ precisely to the expression‑muscle areas that cause unwanted lines and wrinkles — gently, effectively and without injections.
We use Mesoskinline equipment and products
Across all courses we work exclusively with Mesoskinline® products and equipment — a specialised, internationally recognised European concept created through Danish‑German‑Italian collaboration and considered a leader in non‑invasive mesotherapy.
Each treatment is calibrated with precise viscosities and dosages so you can work safely and effectively.
Equipment included in course
MESOpower® Pen Kit
This Pen represents the latest generation tool using nano-infusion technology used in microneedling procedures
See Video PresentationIt is equipped with a powerful steel motor that drives the needles precisely and vertically—with no side vibrations. The result is exceptionally controlled, even stimulation for maximum efficiency and comfort.
It sets a new standard and surpasses traditional rollers with far greater precision and advanced technology.
Total value: £490,00 (Included in the course price)
Treatments are performed only with the specialized MESOpower® Pen.
International certification
International standardization:
CPD certification documents that the training is developed and delivered in accordance with globally recognized quality requirements for professional development.
Recognized CPD certificate:
The certificate serves as official proof of your qualifications, recognized by professional organizations and partners worldwide.
Professional credibility and continuity:
The certification emphasizes your commitment to continuous learning, up‑to‑date knowledge and responsible practice—benefiting both clients and clinic.
What is the MESO BOTO‑Xtreme+ treatment?
MESO BOTO‑Xtreme+ — an effective botulinum alternative without side effects
MESO BOTO‑Xtreme+ is an advanced, non‑invasive mesotherapy treatment that restructures and firms the skin from within to restore a youthful look.
The formulation combines biomimetic peptides such as Argireline®, SNAP‑8 and Leuphasyl® with hyaluronic acid and retinol, helping reduce fine lines, stimulate regeneration and improve firmness, tone and elasticity. It also delivers intensive hydration, antioxidants and nutrients for a more even, vital appearance.
Botulinum‑like effect — without the risks
Active peptides modulate SNAP‑25 in the SNARE complex, attenuating acetylcholine release. The result is relaxation of expression muscles and fibroblasts, reducing contractions and smoothing wrinkles — without the side effects associated with Botox.
How MESO BOTO‑Xtreme+ works on muscles and skin
It regulates facial muscle activity. This tonal modulation dampens neurons that control nerve impulses, which underpins the smoothing and firming effect on the skin.
Normally muscles contract when neurotransmitters carried in small vesicles are released. Before the signal is released, a protein complex — the SNARE complex — forms between the vesicle and the cell membrane.
The SNARE complex, consisting of VAMP, syntaxin and SNAP‑25, enables the vesicle to fuse with the neuron membrane and release acetylcholine into the synapse, triggering contraction.
By modulating this mechanism, MESO BOTO‑Xtreme+ reduces acetylcholine release, lowers muscle activity and visibly smooths the skin.
We use Mesoskinline equipment and products
Across all courses, we work exclusively with Mesoskinline® products and devices—a specialized and internationally recognized European concept, developed in Danish‑German‑Italian collaboration and regarded as a leader in non‑invasive mesotherapy.
Each treatment is carefully matched with precise consistencies and dosages so you can work both safely and efficiently.
Manufactured in the EU under ISO 9001 and ISO 13485—compliant with European quality and safety standards.
Dermatologically tested meso‑cocktails developed for non‑invasive use (non‑medical products).
A strong supplier network and professional training, used in 50+ countries, gives you a safe entry into clinical practice.
You get access to:
Experience from leading clinics – methods used daily around the globe.
Proven products and protocols – with safety and efficacy in focus.
International recognition – training that strengthens your CV and increases your attractiveness as a practitioner.
Confidence starting out – close guidance and materials that help you implement the treatment safely in your own clinic.
Fine and deep lines, wrinkles and laxity
Dehydrated skin and dull complexion
Scars (including acne), uneven pigmentation and dark spots
Enlarged pores
Stretch marks
Hair loss and stimulation of scalp and hair growth
Bags and dark circles under the eyes
